Lataa...
Allosteric modulators restore orthosteric agonist binding to mutated CB(1) receptors
OBJECTIVES: To determine if diminished orthosteric agonist binding due to mutations in extracellular loops 1 or 2 of the cannabinoid receptor 1 (CB(1)) can be overcome by an allosteric modulator and restore agonist binding. METHODS: Binding assays were performed using a range of concentrations of or...
Tallennettuna:
| Julkaisussa: | J Pharm Pharmacol |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2019
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6906232/ https://ncbi.nlm.nih.gov/pubmed/31722122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jphp.13193 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|