Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer

Emerging evidence suggests that dysregulation of oncogenic pathways requires precise tuning in order for cancer to develop. To test this, we examined the overlap between cis-acting elements of the hypoxia-inducible factor (HIF) pathway and cancer-susceptibility polymorphisms as defined in genome-wid...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Schmid, Virginia, Lafleur, Veronique N., Lombardi, Olivia, Li, Ran, Salama, Rafik, Colli, Leandro, Choudhry, Hani, Chanock, Stephen, Ratcliffe, Peter J., Mole, David R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6904466/
https://ncbi.nlm.nih.gov/pubmed/31822727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-55098-7
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