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Heavy Enzymes and the Rational Redesign of Protein Catalysts
An unsolved mystery in biology concerns the link between enzyme catalysis and protein motions. Comparison between isotopically labelled “heavy” dihydrofolate reductases and their natural‐abundance counterparts has suggested that the coupling of protein motions to the chemistry of the catalysed react...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900096/ https://ncbi.nlm.nih.gov/pubmed/31016852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900134 |
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