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Heavy Enzymes and the Rational Redesign of Protein Catalysts
An unsolved mystery in biology concerns the link between enzyme catalysis and protein motions. Comparison between isotopically labelled “heavy” dihydrofolate reductases and their natural‐abundance counterparts has suggested that the coupling of protein motions to the chemistry of the catalysed react...
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| 發表在: | Chembiochem |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6900096/ https://ncbi.nlm.nih.gov/pubmed/31016852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900134 |
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