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Heavy Enzymes and the Rational Redesign of Protein Catalysts

An unsolved mystery in biology concerns the link between enzyme catalysis and protein motions. Comparison between isotopically labelled “heavy” dihydrofolate reductases and their natural‐abundance counterparts has suggested that the coupling of protein motions to the chemistry of the catalysed react...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chembiochem
Päätekijät: Scott, Alan F., Luk, Louis Y.‐P., Tuñón, Iñaki, Moliner, Vicent, Allemann, Rudolf K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900096/
https://ncbi.nlm.nih.gov/pubmed/31016852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900134
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