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Rational redesign of the folding pathway of a modular protein
The modular structures of repeat proteins afford them distinct properties compared with globular proteins, enabling them to function in a large and diverse range of cellular processes. Here, we show that they can also have different folding mechanisms. Myotrophin comprises four ankyrin repeats stack...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815241/ https://ncbi.nlm.nih.gov/pubmed/17299057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604653104 |
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