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Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry

The differential scanning fluorimetry (DSF) screening of 5.692 fragments in combination with benzenesulfonamide (BSA) against bovine carbonic anhydrase (bCA) delivered >100 hits that either caused, on their own, a significant thermal shift (ΔT(m), °C) in the protein melting temperature or signifi...

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Bibliografische gegevens
Gepubliceerd in:J Enzyme Inhib Med Chem
Hoofdauteurs: Krasavin, Mikhail, Kalinin, Stanislav, Zozulya, Sergey, Gryniukova, Anastasiia, Borysko, Petro, Angeli, Andrea, Supuran, Claudiu T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6896451/
https://ncbi.nlm.nih.gov/pubmed/31797704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1698562
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