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Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry
The differential scanning fluorimetry (DSF) screening of 5.692 fragments in combination with benzenesulfonamide (BSA) against bovine carbonic anhydrase (bCA) delivered >100 hits that either caused, on their own, a significant thermal shift (ΔT(m), °C) in the protein melting temperature or signifi...
Enregistré dans:
| Publié dans: | J Enzyme Inhib Med Chem |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6896451/ https://ncbi.nlm.nih.gov/pubmed/31797704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1698562 |
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