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CD4(+) T cell help creates memory CD8(+) T cells with innate and help-independent recall capacities
CD4(+) T cell help is required for the generation of CD8(+) cytotoxic T lymphocyte (CTL) memory. Here, we use genome-wide analyses to show how CD4(+) T cell help delivered during priming promotes memory differentiation of CTLs. Help signals enhance IL-15-dependent maintenance of central memory T (T(...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6892909/ https://ncbi.nlm.nih.gov/pubmed/31797935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13438-1 |
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