The CD4 (+) T-cell help signal is transmitted from APC to CD8 (+) T-cells via CD27–CD70 interactions

CD8 (+) cytotoxic T lymphocytes are critical components of immunity against infectious pathogens, tumours, and in the case of pathogenic autoimmunity, normal self tissues. CD4 (+) T (T(H)) cells provide ‘help’ to CD8 (+) cytotoxic T lymphocytes during priming by first activating antigen-presenting c...

Full description

Saved in:
Bibliographic Details
Main Authors: Feau, Sonia, Garcia, Zacarias, Arens, Ramon, Yagita, Hideo, Borst, Jannie, Schoenberger, Stephen P.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606886/
https://ncbi.nlm.nih.gov/pubmed/22781761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1948
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items