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Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells
Two competing theories have been put forward to explain the role of CD4(+) T cells in priming CD8(+) memory T cells: one proposes paracrine secretion of interleukin 2 (IL-2); the other proposes the activation of antigen-presenting cells (APCs) via the costimulatory molecule CD40 and its ligand CD40L...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388550/ https://ncbi.nlm.nih.gov/pubmed/21804558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2079 |
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