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Autocrine IL-2 is required for secondary population expansion of CD8(+) memory T cells

Two competing theories have been put forward to explain the role of CD4(+) T cells in priming CD8(+) memory T cells: one proposes paracrine secretion of interleukin 2 (IL-2); the other proposes the activation of antigen-presenting cells (APCs) via the costimulatory molecule CD40 and its ligand CD40L...

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Bibliografiska uppgifter
Huvudupphovsmän: Feau, Sonia, Arens, Ramon, Togher, Susan, Schoenberger, Stephen P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388550/
https://ncbi.nlm.nih.gov/pubmed/21804558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2079
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