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The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in mice
Induction of CD8(+) T cell immunity is a key characteristic of an effective vaccine. For safety reasons, human vaccination strategies largely use attenuated nonreplicating or weakly replicating poxvirus-based vectors, but these often elicit poor CD8(+) T cell immunity and might not result in optimal...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3007137/ https://ncbi.nlm.nih.gov/pubmed/21183789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI42056 |
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