OX40 Drives Protective Vaccinia Virus-Specific CD8 T cells

Vaccinia virus (VACV) affords long lasting protection against variola virus, the agent of smallpox. VACV-reactive CD8 T cells contribute to protection but their molecular control is unknown. We show that the TNFR molecule OX40 (CD134) controls primary VACV-specific CD8 T cell expansion and anti-vira...

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Main Authors: Salek-Ardakani, Shahram, Moutaftsi, Magdalini, Crotty, Shane, Sette, Alessandro, Croft, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729132/
https://ncbi.nlm.nih.gov/pubmed/19017988
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