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T cells compete by cleaving cell surface CD27 and blocking access to CD70 bearing APCs

T cells compete against each other for access to molecules on antigen presenting cells (APC) in addition to peptide:MHC complexes. However, the identity of cell surface molecules that influence T cell competition, other than peptide:MHC, have yet to be defined. Here we identify CD70, a TNF ligand ex...

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Publicat a:Eur J Immunol
Autors principals: Burchill, Matthew A., Tamburini, Beth A., Kedl, Ross M.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674305/
https://ncbi.nlm.nih.gov/pubmed/26179759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201545749
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