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T Cells Compete for Access to Antigen-Bearing Antigen-Presenting Cells

These studies tested whether antigenic competition between T cells occurs. We generated CD8(+) T cell responses in H-2(b) mice against the dominant ovalbumin epitope SIINFEKL (ova8) and subdominant epitope KRVVFDKL, using either vaccinia virus expressing ovalbumin (VV-ova) or peptide-pulsed dendriti...

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Détails bibliographiques
Auteurs principaux: Kedl, Ross M., Rees, William A., Hildeman, David A., Schaefer, Brian, Mitchell, Tom, Kappler, John, Marrack, Philippa
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2195874/
https://ncbi.nlm.nih.gov/pubmed/11034600
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