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Blocking CD27-CD70 costimulatory pathway suppresses experimental colitis
The pathogenesis of human inflammatory bowel disease (IBD) and most experimental models of IBD is dependent on the activation and expansion of CD4(+) T cells via interaction with mucosal antigen-presenting cells. The costimulatory receptor CD70 is transiently expressed on the surface of conventional...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4232384/ https://ncbi.nlm.nih.gov/pubmed/19525396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802424 |
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