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IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell–Dependent Route

Type I IFN is produced upon infection and tissue damage and induces the expression of many IFN-stimulated genes (ISGs) that encode host-protective proteins. ISG15 is a ubiquitin-like molecule that can be conjugated to proteins but is also released from cells in a free form. Free, extracellular ISG15...

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Publicat a:J Immunol
Autors principals: Iglesias-Guimarais, Victoria, Ahrends, Tomasz, de Vries, Evert, Knobeloch, Klaus-Peter, Volkov, Andriy, Borst, Jannie
Format: Artigo
Idioma:Inglês
Publicat: AAI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7128311/
https://ncbi.nlm.nih.gov/pubmed/32169846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901410
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