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HMGB1, an innate alarmin, in the pathogenesis of type 1 diabetes

HMGB1, an evolutionarily conserved chromosomal protein, was recently re-discovered to act as a “danger signal” (alarmin) to alert the innate immune system for the initiation of host defense or tissue repair. Extracellular HMGB1 can be either passively released from damaged/necrotic cells or secreted...

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Detalhes bibliográficos
Main Authors: Zhang, Shu, Zhong, Jixin, Yang, Ping, Gong, Feili, Wang, Cong-Yi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776260/
https://ncbi.nlm.nih.gov/pubmed/19918326
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