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The opposing roles of CD4(+) T cells in anti‐tumour immunity

Cancer immunotherapy focuses mainly on anti‐tumour activity of CD8(+) cytotoxic T lymphocytes (CTLs). CTLs can directly kill all tumour cell types, provided they carry recognizable antigens. However, CD4(+) T cells also play important roles in anti‐tumour immunity. CD4(+) T cells can either suppress...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Ahrends, Tomasz, Borst, Jannie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050207/
https://ncbi.nlm.nih.gov/pubmed/29700809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12941
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