Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3

Upon necroptosis activation, receptor interacting serine/threonine kinase (RIPK)1 and RIPK3 form a necrosome complex with pseudokinase mixed lineage kinase-like (MLKL). Although protein phosphorylation is a key event for RIPK1 and RIPK3 activation in response to a necroptosis signal, relatively litt...

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Publicado no:Cell Death Dis
Main Authors: Lee, Song-Yi, Kim, Hyunjoo, Li, Cathena Meiling, Kang, Jaemin, Najafov, Ayaz, Jung, Muhah, Kang, Soosung, Wang, Shaomeng, Yuan, Junying, Jung, Yong-Keun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6892881/
https://ncbi.nlm.nih.gov/pubmed/31801942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2146-4
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