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Necroptosis in development and diseases

Necroptosis, a form of regulated necrotic cell death mediated by RIPK1 (receptor-interacting protein kinase 1) kinase activity, RIPK3, and MLKL (mixed-lineage kinase domain-like pseudokinase), can be activated under apoptosis-deficient conditions. Modulating the activation of RIPK1 by ubiquitination...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Shan, Bing, Pan, Heling, Najafov, Ayaz, Yuan, Junying
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900707/
https://ncbi.nlm.nih.gov/pubmed/29593066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.312561.118
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