Activation of necroptosis in multiple sclerosis

Multiple sclerosis (MS), a common neurodegenerative disease of the CNS, is characterized by the loss of oligodendrocytes and demyelination. TNFα, a proinflammatory cytokine implicated in MS, can activate necroptosis, a necrotic cell death pathway regulated by RIPK1 and RIPK3 under caspase-8 deficien...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Ofengeim, Dimitry, Ito, Yasushi, Najafov, Ayaz, Zhang, Yaoyang, Shan, Bing, DeWitt, Judy Park, Ye, Juanying, Zhang, Xumin, Chang, Ansi, Vakifahmetoglu-Norberg, Helin, Geng, Jiefei, Py, Benedicte, Zhou, Wen, Amin, Palak, Lima, Jonilson Berlink, Qi, Chunting, Yu, Qiang, Trapp, Bruce, Yuan, Junying
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4494996/
https://ncbi.nlm.nih.gov/pubmed/25801023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.051
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