Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain

Molecular mechanisms that define patterns of neuropeptide expression are essential for the formation and rewiring of neural circuits. The prodynorphin gene (PDYN) gives rise to dynorphin opioid peptides mediating depression and substance dependence. We here demonstrated that PDYN is expressed in neu...

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Publicat a:Cereb Cortex
Autors principals: Bazov, Igor, Sarkisyan, Daniil, Kononenko, Olga, Watanabe, Hiroyuki, Taqi, Mumtaz Malik, Stålhandske, Lada, Verbeek, Dineke S, Mulder, Jan, Rajkowska, Grazyna, Sheedy, Donna, Kril, Jillian, Sun, Xueguang, Syvänen, Ann-Christine, Yakovleva, Tatiana, Bakalkin, Georgy
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6887740/
https://ncbi.nlm.nih.gov/pubmed/28968778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhx181
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