Conformation Effects of CpG Methylation on Single-Stranded DNA Oligonucleotides: Analysis of the Opioid Peptide Dynorphin-Coding Sequences

Single-stranded DNA (ssDNA) is characterized by high conformational flexibility that allows these molecules to adopt a variety of conformations. Here we used native polyacrylamide gel electrophoresis (PAGE), circular dichroism (CD) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy to sh...

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Detalhes bibliográficos
Main Authors: Taqi, Malik Mumtaz, Wärmländer, Sebastian K. T. S., Yamskova, Olga, Madani, Fatemeh, Bazov, Igor, Luo, Jinghui, Zubarev, Roman, Verbeek, Dineke, Gräslund, Astrid, Bakalkin, Georgy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387154/
https://ncbi.nlm.nih.gov/pubmed/22768096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039605
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