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Formulation of vaccines containing CpG oligonucleotides and alum
CpG oligodeoxynucleotides are potent immunostimulants. For parenterally delivered alum based vaccines, the immunostimulatory effect of CpG depends on the association of the CpG and antigen to the alum. We describe effects of buffer components on the binding of CPG 7909 to aluminum hydroxide (Alhydro...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2001166/ https://ncbi.nlm.nih.gov/pubmed/17512533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2007.04.003 |
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