OPIOID PRECURSOR PROTEIN ISOFORM IS TARGETED TO THE CELL NUCLEI IN THE HUMAN BRAIN

BACKGROUND: Neuropeptide precursors are traditionally viewed as proteins giving rise to small neuropeptide molecules. Prodynorphin (PDYN) is the precursor protein to dynorphins, endogenous ligands for the κ-opioid receptor. Alternative mRNA splicing of neuropeptide genes may regulate cell- and tissu...

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Publicado no:Biochim Biophys Acta
Main Authors: Kononenko, Olga, Bazov, Igor, Watanabe, Hiroyuki, Gerashchenko, Ganna, Dyachok, Oleg, Verbeek, Dineke S., Alkass, Kanar, Druid, Henrik, Andersson, Malin, Mulder, Jan, Svenningsen, Åsa Fex, Rajkowska, Grazyna, Stockmeier, Craig A., Krishtal, Oleg, Yakovleva, Tatiana, Bakalkin, Georgy
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323248/
https://ncbi.nlm.nih.gov/pubmed/27838394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.11.002
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