Downregulation of the endogenous opioid peptides in the dorsal striatum of human alcoholics

The endogenous opioid peptides dynorphins and enkephalins may be involved in brain-area specific synaptic adaptations relevant for different stages of an addiction cycle. We compared the levels of prodynorphin (PDYN) and proenkephalin (PENK) mRNAs (by qRT-PCR), and dynorphins and enkephalins (by rad...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Sarkisyan, Daniil, Hussain, Muhammad Z., Watanabe, Hiroyuki, Kononenko, Olga, Bazov, Igor, Zhou, Xingwu, Yamskova, Olga, Krishtal, Oleg, Karpyak, Victor M., Yakovleva, Tatiana, Bakalkin, Georgy
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4428131/
https://ncbi.nlm.nih.gov/pubmed/26029055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00187
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