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Copper Inhibits the AlkB Family DNA Repair Enzymes under Wilson’s Disease Condition

Disturbed metabolism of copper ions can cause diseases such as Wilson’s disease (WD). In this work, we investigated the inhibitory effect of Cu(II) ion in vitro on the AlkB family DNA repair enzymes, which are members of the Fe(II)/alpha-ketoglutarate-dependent dioxygenase and include human ALKBH2,...

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Bibliografski detalji
Izdano u:Chem Res Toxicol
Glavni autori: Bian, Ke, Chen, Fangyi, Humulock, Zachary T., Tang, Qi, Li, Deyu
Format: Artigo
Jezik:Inglês
Izdano: 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885016/
https://ncbi.nlm.nih.gov/pubmed/28926697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.7b00230
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