Dynamic states of the DNA repair enzyme AlkB regulate product release

The 2-oxoglutarate (2OG)- and Fe(2+)-dependent dioxygenase AlkB couples the demethylation of modified DNA to the decarboxylation of 2OG. Extensive crystallographic analyses have shown no evidence of significant structural differences between complexes binding either 2OG or succinate. By using nuclea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bleijlevens, Boris, Shivarattan, Tara, Flashman, Emily, Yang, Yi, Simpson, Pete J, Koivisto, Pertti, Sedgwick, Barbara, Schofield, Christopher J, Matthews, Steve J
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2008
Pynciau:
Scientific Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529343/
https://ncbi.nlm.nih.gov/pubmed/18617893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.120
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