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Transient kinetic analysis of oxidative dealkylation by the direct reversal DNA repair enzyme AlkB

AlkB is a bacterial Fe(II)– and 2-oxoglutarate–dependent dioxygenase that repairs a wide range of alkylated nucleobases in DNA and RNA as part of the adaptive response to exogenous nucleic acid–alkylating agents. Although there has been longstanding interest in the structure and specificity of Esche...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Baldwin, Michael R., Admiraal, Suzanne J., O'Brien, Patrick J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2020
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7247310/
https://ncbi.nlm.nih.gov/pubmed/32284330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013517
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