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Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA
Escherichia coli AlkB and its human homologues ABH2 and ABH3 repair DNA/RNA base lesions by using a direct oxidative dealkylation mechanism. ABH2 has the primary role of guarding mammalian genomes against 1-meA damage by repairing this lesion in double-stranded DNA (dsDNA), whereas AlkB and ABH3 pre...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587245/ https://ncbi.nlm.nih.gov/pubmed/18432238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06889 |
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