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Characterization of six recombinant human RNase H2 bearing Aicardi-Goutiéres syndrome causing mutations
Mammalian RNase H2 is a heterotrimeric enzyme consisting of one catalytic subunit (A) and two accessory subunits (B and C). RNase H2 is involved in the removal of a single ribonucleotide embedded in genomic DNA and removal of RNA of RNA/DNA hybrids. In humans, mutation of the RNase H2 gene causes a...
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| Publicado no: | J Biochem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6882408/ https://ncbi.nlm.nih.gov/pubmed/31529068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvz073 |
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