Genome Instability Consequences of RNase H2 Aicardi-Goutières Syndrome Alleles

Antzeko izenburuak

• Reduction of hRNase H2 activity in Aicardi–Goutières syndrome cells leads to replication stress and genome instability
  nork: Pizzi, Sara, et al.
  Argitaratua: (2015)
• Functional Consequences of the RNase H2A Subunit Mutations That Cause Aicardi-Goutières Syndrome
  nork: Coffin, Stephanie R., et al.
  Argitaratua: (2011)
• RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases
  nork: Perrino, Fred W., et al.
  Argitaratua: (2008)
• Increased spontaneous recombination in RNase H2-deficient cells arises from multiple contiguous rNMPs and not from single rNMP residues incorporated by DNA polymerase epsilon
  nork: Epshtein, Anastasiya, et al.
  Argitaratua: (2016)
• Increased spontaneous recombination in RNase H2-deficient cells arises from multiple contiguous rNMPs and not from single rNMP residues incorporated by DNA polymerase epsilon
  nork: Anastasiya Epshtein, et al.
  Argitaratua: (2016-05-01)