RNase H2, mutated in Aicardi‐Goutières syndrome, promotes LINE‐1 retrotransposition

Long INterspersed Element class 1 (LINE‐1) elements are a type of abundant retrotransposons active in mammalian genomes. An average human genome contains ~100 retrotransposition‐competent LINE‐1s, whose activity is influenced by the combined action of cellular repressors and activators. TREX1, SAMHD...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Benitez‐Guijarro, Maria, Lopez‐Ruiz, Cesar, Tarnauskaitė, Žygimantė, Murina, Olga, Mian Mohammad, Mahwish, Williams, Thomas C, Fluteau, Adeline, Sanchez, Laura, Vilar‐Astasio, Raquel, Garcia‐Canadas, Marta, Cano, David, Kempen, Marie‐Jeanne HC, Sanchez‐Pozo, Antonio, Heras, Sara R, Jackson, Andrew P, Reijns, Martin AM, Garcia‐Perez, Jose L
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068448/
https://ncbi.nlm.nih.gov/pubmed/29959219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201798506
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker