Val143 of human ribonuclease H2 is not critical for, but plays a role in determining catalytic activity and substrate specificity

Ribonuclease H2 (RNase H2) exhibits both single ribonucleotide excision activity (activity A) and RNA strand degrading activity (activity B). Val143 of human RNase H2 is located at the active site and is conserved in eukaryotic RNase H2. In this study, we explored the role of Val143 in catalytic act...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Baba, Misato, Kojima, Kenji, Nishimura, Takuto, Sugiura, Takuya, Takita, Teisuke, Uehara, Ryo, Crouch, Robert J., Yasukawa, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028304/
https://ncbi.nlm.nih.gov/pubmed/32069311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228774
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados