Effects of neutral salts and pH on the activity and stability of human RNase H2

Ribonuclease H (RNase H) specifically degrades the RNA of RNA/DNA hybrid. Recent study has shown that a single ribonucleotide is embedded in DNA double strand at every few thousand base pairs in human genome, and human RNase H2 is involved in its removal. Here, we examined the effects of neutral sal...

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Detalhes bibliográficos
Publicado no:J Biochem
Main Authors: Baba, Misato, Kojima, Kenji, Nakase, Rihoko, Imai, Shota, Yamasaki, Tomomi, Takita, Teisuke, Crouch, Robert J., Yasukawa, Kiyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Regular Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5892398/
https://ncbi.nlm.nih.gov/pubmed/28402412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvx021
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