Human CD8(+) Tregs expressing a MHC-specific CAR display enhanced suppression of human skin rejection and GVHD in NSG mice

Polyclonal CD8(+)CD45RC(low/−) Tregs are potent regulatory cells able to control solid organ transplantation rejection and even induce tolerance. However, donor major histocompatibility complex (MHC)–specific Tregs are more potent than polyclonal Tregs in suppressing T-cell responses and preventing...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Bézie, Séverine, Charreau, Béatrice, Vimond, Nadège, Lasselin, Juliette, Gérard, Nathalie, Nerrière-Daguin, Véronique, Bellier-Waast, Frédérique, Duteille, Franck, Anegon, Ignacio, Guillonneau, Carole
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2019
Fag:
Immunobiology and Immunotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880915/
https://ncbi.nlm.nih.gov/pubmed/31730699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000411
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker