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Genetic engineering of human and mouse CD4(+) and CD8(+) Tregs using lentiviral vectors encoding chimeric antigen receptors

The last decade has seen a significant increase of cell therapy protocols using effector T cells (Teffs) in particular, but also, more recently, non-engineered and expanded polyclonal regulatory T cells (Tregs) to control pathological immune responses such as cancer, autoimmune diseases, or transpla...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther Methods Clin Dev
Hauptverfasser: Vimond, Nadège, Lasselin, Juliette, Anegon, Ignacio, Guillonneau, Carole, Bézie, Séverine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7749301/
https://ncbi.nlm.nih.gov/pubmed/33376756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.11.008
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