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IL-34 is a Treg-specific cytokine and mediates transplant tolerance

Cytokines and metabolic pathway–controlling enzymes regulate immune responses and have potential as powerful tools to mediate immune tolerance. Blockade of the interaction between CD40 and CD40L induces long-term cardiac allograft survival in rats through a CD8(+)CD45RC(lo) Treg potentiation. Here,...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Bézie, Séverine, Picarda, Elodie, Ossart, Jason, Tesson, Laurent, Usal, Claire, Renaudin, Karine, Anegon, Ignacio, Guillonneau, Carole
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607123/
https://ncbi.nlm.nih.gov/pubmed/26389674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81227
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