eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus

Newcastle disease virus (NDV) causes severe infectious disease in poultry and selectively kills tumor cells, by inducing apoptosis and cytokines secretion. In this report, we study the mechanisms underlying NDV-induced apoptosis by investigating the unfolded protein response (UPR). We found that NDV...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Li, Yanrong, Jiang, Weiyu, Niu, Qiaona, Sun, Yingjie, Meng, Chunchun, Tan, Lei, Song, Cuiping, Qiu, Xusheng, Liao, Ying, Ding, Chan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877643/
https://ncbi.nlm.nih.gov/pubmed/31767828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2128-6
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