eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus

Newcastle disease virus (NDV) causes severe infectious disease in poultry and selectively kills tumor cells, by inducing apoptosis and cytokines secretion. In this report, we study the mechanisms underlying NDV-induced apoptosis by investigating the unfolded protein response (UPR). We found that NDV...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Li, Yanrong, Jiang, Weiyu, Niu, Qiaona, Sun, Yingjie, Meng, Chunchun, Tan, Lei, Song, Cuiping, Qiu, Xusheng, Liao, Ying, Ding, Chan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877643/
https://ncbi.nlm.nih.gov/pubmed/31767828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2128-6
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