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ER stress signalling through eIF2α and CHOP, but not IRE1α, attenuates adipogenesis in mice
AIMS/HYPOTHESIS: Although obesity is associated with endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) in adipose tissue, it is not known how UPR signalling affects adipogenesis. To test whether signalling through protein kinase RNA-like ER kinase/eukaryotic ini...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3606029/ https://ncbi.nlm.nih.gov/pubmed/23314846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2809-5 |
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