The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis

The endoplasmic reticulum (ER) is the cellular organelle responsible for protein folding and assembly, lipid and sterol biosynthesis, and calcium storage. The unfolded protein response (UPR) is an adaptive intracellular stress response to accumulation of unfolded or misfolded proteins in the ER. In...

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Bibliographic Details
Main Authors: Zhang, Kezhong, Wang, Shiyu, Malhotra, Jyoti, Hassler, Justin R, Back, Sung Hoon, Wang, Guohui, Chang, Lin, Xu, Wenbo, Miao, Hongzhi, Leonardi, Roberta, Chen, Y Eugene, Jackowski, Suzanne, Kaufman, Randal J
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094110/
https://ncbi.nlm.nih.gov/pubmed/21407177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.52
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