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Domain compatibility in Ire1 kinase is critical for the Unfolded Protein Response
The unfolded phrotein response is a mechanism to cope with endoplasmic reticulum stress. In Saccharomyces cerevisiae, Ire1 senses the stress and mediates a signaling cascade to upregulate responsive genes through an unusual HAC1 mRNA splicing. The splicing requires interconnected activity (kinase an...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3762510/ https://ncbi.nlm.nih.gov/pubmed/20541549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.06.003 |
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