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Functional analysis of the mammalian RNA ligase for IRE1 in the unfolded protein response
The unfolded protein response (UPR) is a conserved signalling pathway activated on the accumulation of unfolded proteins within the endoplasmic reticulum (ER), termed ER stress. Upon ER stress, HAC1/XBP1 undergoes exon/intron-specific excision by inositol requiring enzyme 1 (IRE1) to remove an intro...
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| Publicado en: | Biosci Rep |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Portland Press Ltd.
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5333776/ https://ncbi.nlm.nih.gov/pubmed/28093457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20160574 |
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