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IRE1α nucleotide sequence cleavage specificity in the unfolded protein response

Inositol requiring enzyme 1 (IRE1) is a conserved sensor of the unfolded protein response (UPR) that has protein kinase and endoribonuclease (RNase) enzymatic activities and thereby initiates HAC1/XBP1 splicing. Previous studies demonstrated that human IRE1α (hIRE1α) does not cleave S. cerevisiae HA...

詳細記述

保存先:
書誌詳細
出版年:FEBS Lett
主要な著者: Poothong, Juthakorn, Sopha, Pattarawut, Kaufman, Randal J., Tirasophon, Witoon
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5436603/
https://ncbi.nlm.nih.gov/pubmed/28027394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12546
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