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IRE1α nucleotide sequence cleavage specificity in the unfolded protein response
Inositol requiring enzyme 1 (IRE1) is a conserved sensor of the unfolded protein response (UPR) that has protein kinase and endoribonuclease (RNase) enzymatic activities and thereby initiates HAC1/XBP1 splicing. Previous studies demonstrated that human IRE1α (hIRE1α) does not cleave S. cerevisiae HA...
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| Publicado no: | FEBS Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436603/ https://ncbi.nlm.nih.gov/pubmed/28027394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12546 |
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