PCV2 and PRV Coinfection Induces Endoplasmic Reticulum Stress via PERK-eIF2α-ATF4-CHOP and IRE1-XBP1-EDEM Pathways

Porcine circovirus 2 (PCV2) and pseudorabies virus (PRV) are two important pathogens in the pig industry. PCV2 or PRV infection can induce endoplasmic reticulum stress (ERS) and unfolded protein response (UPR). However, the effect of PCV2 and PRV coinfection on the ERS and UPR pathways remains uncle...

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Main Authors: Si Chen, Xue Li, Xinwei Zhang, Guyu Niu, Lin Yang, Weilong Ji, Liying Zhang, Linzhu Ren
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-04-01
Serier:International Journal of Molecular Sciences
Fag:
porcine circovirus type 2
porcine pseudorabies virus
coinfection
endoplasmic reticulum stress (ERS)
transcriptome sequencing
Online adgang:https://www.mdpi.com/1422-0067/23/9/4479
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