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Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway
Mammalian inositol-requiring enzyme 1α (IRE1α) is the most conserved of all endoplasmic reticulum (ER) stress sensors, which includes activating transcription factor (ATF) 6 and double-stranded RNA-dependent protein kinase (PKR)-like ER kinase (PERK). IRE1α has been known to splice X-box binding pro...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4823713/ https://ncbi.nlm.nih.gov/pubmed/27052593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24217 |
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