eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus

Newcastle disease virus (NDV) causes severe infectious disease in poultry and selectively kills tumor cells, by inducing apoptosis and cytokines secretion. In this report, we study the mechanisms underlying NDV-induced apoptosis by investigating the unfolded protein response (UPR). We found that NDV...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Yanrong, Jiang, Weiyu, Niu, Qiaona, Sun, Yingjie, Meng, Chunchun, Tan, Lei, Song, Cuiping, Qiu, Xusheng, Liao, Ying, Ding, Chan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877643/
https://ncbi.nlm.nih.gov/pubmed/31767828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-2128-6
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